Explore the Fast Company Middle East’s Most Innovative Companies 2025 list, featuring 56 winning entries reshaping businesses and industries. We’ve selected the companies making the most significant impact with their initiatives across 24 categories, including the most innovative AI and data science, sustainability, energy, finance & fintech, and women-backed companies.

Innovation in healthcare turns complexity into actionable solutions. Data, AI, and new treatments empower providers to anticipate, personalize, and improve patient outcomes. These companies are leveraging technology to enhance efficiency, accessibility, and impact. They are making healthcare proactive, connected, and intelligent. 

Aster DM Healthcare

For patient-centered, connected healthcare

Aster DM Healthcare has transformed healthcare by creating a fully integrated ecosystem that places patients at the center of every interaction. Over the past two years, the company launched the myAster app, the region’s first comprehensive health, wellness, and beauty platform, connecting users with doctors, diagnostics, pharmacies, and wellness services. myAster delivers AI-driven symptom analysis, Arabic voice response, e-prescriptions, home care, and personalized wellness recommendations, improving the accessibility and continuity of care. Beyond digital tools, Aster has integrated advanced technologies across its Smart Hospital network, including robotic-assisted surgeries, AI diagnostics, predictive analytics, and unified electronic health records. By combining digital innovation, clinical excellence, and operational efficiency, Aster has developed a sustainable, inclusive healthcare model that reduces environmental impact, expands access to care, and sets new standards for patient-centered care.

M42

For AI-driven precision healthcare and longevity

M42 has strengthened its position as a leader in health technology by integrating AI, genomics, and clinical expertise into a connected, data-driven healthcare ecosystem. Over the past year, the organization has launched major initiatives, including the Jordan Digital Health Center, which links five remote hospitals to a central command hub, and the Abu Dhabi Biobank, which introduced the UAE’s first private cord blood storage service. Cleveland Clinic Abu Dhabi has continued to pioneer AI-enabled diagnostics and advanced procedures such as minimally invasive thoracic aortic repair and robotic lung transplants. M42’s Med42-v2, an open-access clinical large language model, achieved 87.3 percent accuracy on USMLE-style questions, contributing to global medical AI research. The Emirati Genome Programme has surpassed 850,000 whole genomes sequenced, advancing personalized medicine and research into rare diseases. Across its network, M42 utilizes AI-assisted diagnostics, adaptive radiotherapy, and predictive analytics to enhance patient outcomes. Meanwhile, Malaffi, the region’s first health information exchange, connects 12.7 million patients and 3.5 billion clinical records, enabling coordinated and preventive care.

M42 connects AI, genomics, and clinical expertise across healthcare networks, including the Jordan Digital Health Center and Abu Dhabi Biobank, supporting precision medicine, AI-assisted diagnostics, and preventive care.

PureHealth

For integrated, AI-powered healthcare and longevity

PureHealth has strengthened its position as a global leader in the healthcare industry. Internationally, the Group expanded through the acquisitions of Hellenic Healthcare Group in Greece and Cyprus, the integration of the UK’s Circle Health Group, and continued investment in Ardent Health Services in the US, now operating more than 110 hospitals across five countries. In the UAE, PureHealth advanced specialist and preventive care through SEHA’s transplant expansion, SSMC’s new diagnostic centres, and the nationwide rollout of the AI-enabled Pura app, which supports 600,000 users with virtual consultations and mental health services through Sakina. The Pura Longevity Clinic introduced AI-driven preventive care, while innovations such as PureLab for advanced diagnostics and Circle Health’s robotic surgery network improved clinical outcomes. PureHealth’s Care and Cover model integrates healthcare delivery and insurance, enhancing efficiency, personalization, and accessibility while driving environmental, social, and economic sustainability.